Fig. 1: Visual discrimination training recovers visual functions in chronic cortically-blind (CB) fields. | Nature Communications

Fig. 1: Visual discrimination training recovers visual functions in chronic cortically-blind (CB) fields.

From: Spared perilesional V1 activity underlies training-induced recovery of luminance detection sensitivity in cortically-blind patients

Fig. 1

a, b T1-weighted MRI and full (±21 deg) Humphrey Visual Field (HVF) for two chronic CB patients with stroke-induced damage to the primary visual cortex and associated loss of conscious luminance detection sensitivity. Dark regions (low HVF sensitivity) correspond to blind-field areas. Visual training can successfully restore (a) static orientation discrimination and (b) coarse (left/right) global motion direction discrimination in the blind field of chronic CB patients. Recovery is typically retinotopically-specific, requires weeks of daily home training (blue/green dots in scatter plots), and can be verified in lab under eye-tracking control (red dots in scatter plots). As detailed in previous work21,22,23,24,25, all 11 CB patients included in the present study trained on (c) static orientation discrimination (N = 10) and/or (d) motion direction discrimination (N = 9) at different blind-field locations. All CB patients recovered performance levels on these tasks similar to those at equivalent locations in their intact visual hemifields. Bars show mean performance across subjects (±1 SEM), with individual data superimposed.

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