Table 1 Patient demographics.

From: Spared perilesional V1 activity underlies training-induced recovery of luminance detection sensitivity in cortically-blind patients

Patient

Sex

Age (years)

Damaged hemisphere

Lesion (mm3)

Time post-lesion (months)

Pre-post interval (months)

Pre-training deficit size (deg2)

Post-training improvement (deg2)

Training regime

full HVF

inner 11.5°

full HVF

inner 11.5°

CB1

M

67

L

6,422

10.4

5.5

693 (86%)

133 (51%)

122

40

Double

CB2

F

58

R

16,303

11.8

10.8

294 (37%)

112 (44%)

318

85

Static

CB3

M

63

L

667

38.4

34.4

473 (59%)

100 (38%)

66

51

Double

CB4

F

29

R

2,126

5

3.1

489 (61%)

129 (49%)

49

44

Static

CB5

M

72

L

10,574

11

9.7

764 (95%)

229 (87%)

57

7.4

Double

CB6

F

68

R

64,320

26.2

16.9

194 (24%)

42 (16%)

134

50

Motion

CB7

F

63

L

34,123

10.6

28.3

797 (99%)

253 (96%)

56

56

Double

CB8

M

63

L

3,707

9.1

16.2

598 (74%)

124 (47%)

77

18

Double

CB9

F

52

R

22,880

10.6

30.7

799 (99%)

254 (96%)

13

12

Double

CB10

M

63

L

9,776

237

46.1

704 (87%)

182 (69%)

186

87

Double

CB11

M

77

L

12,500

16.6

23.2

804 (99%)

258 (98%)

117

25

Double

N = 11

5 F | 6 M

61 ± 13

7 L | 4 R

17 K ± 19 K

35 ± 68

20.5 ± 13

601 ± 213 (75%)

165 ± 74 (63%)

109 ± 85

43 ± 27

–

  1. All 11 patients suffered from unilateral, stroke-induced damage to the occipital cortex at least 5 months before training onset, causing a loss in luminance detection sensitivity assessable using Humphrey’s Visual Field (HVF) mapping. Pre-training percent deficit size and post-training improvement area were computed for the full HVF and inner ±11.5 deg (i.e., area stimulated during fMRI). Following visual discrimination training (static orientation, motion direction, or both), all patients showed HVF improvements (i.e., area with ∆HVF ≥ + 6 dB).
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