Fig. 6: Sterilization assessment of drug-resistant bacteria of Fe-Art M.
From: Hedgehog artificial macrophage with atomic-catalytic centers to combat Drug-resistant bacteria
a Schematic illustration for the “capture and killing” function of Fe-Art M by the hedgehog topography and massive generation of ROS on the infective wound skin. b Real-time OD600 values for different samples at 10 µg/mL against MRSA (n = 3 independent experiments per group, data are presented as mean ± SD). c Killing ratio of MRSA treated with V-Art M and Fe-Art M at different concentrations in the presence of H2O2 (n = 3 independent experiments per group, data are presented as mean ± SD). d Digital photographs and e the change of wound sizes on different days (n = 3 independent experiments per group, data are presented as mean ± SD). f HE staining, g Masson and h CD31 staining images of the epidermal histological sections in different groups at day 15. i Number of neutrophils, j collagen index, and k number of blood vessels. In i–k, n = 3 independent experiments and data are represented as mean ± SD. In b, e, i–k, p values are assessed by unpaired Student’s two-sided t-tests compared to the control groups. Experiments were repeated independently (f–h) three times with similar results. Source data are provided as a Source Data file.
