Table 4 Summary of target validation using siRNA knockdown.
From: A comparative analysis of cell surface targeting aptamers
Aptamer | Target | Cell line | Specific knockdown? |
|---|---|---|---|
C2 | TfR | HeLa | Yes |
Waz | TfR | HeLa | Yes |
A9 | PSMA | LnCap | Yes |
A10-3 | PSMA | LnCap | No |
A10-3.2 | PSMA | LnCap | No |
E07.min | EGFR | HeLa | Yes |
CL4 | EGFR | HeLa | No |
SE15-8-mini | Her2 | SkBr3 | No |
2-2(t) | Her2 | SkBr3 | No |
EpDT3 | EpCam | MCF7 | No |
GL21.T | AXL | HeLa | No |
SGC8c | PTK7 | A431 | Yes |
