Fig. 2: GP-FBM can correct for substrate movement to improve estimation of diffusion parameters.
From: Precise measurements of chromatin diffusion dynamics by modeling using Gaussian processes
(a) Scheme showing the measured trajectories of particles r1 and r2 as the combination of substrate motion R and particles' diffusion with respect to the substrate, a1 and a2. (b, c) Distributions of relative errors for the estimation of diffusion parameters on 2000 pairs of simulated trajectories with uniform random parameters (0.1 < Di < 1.1, 0.3 < α < 1, 0.1 < DR < 1.1 and 0.7 < αR < 1.7; dt = 0.5, σ = 0.1 and o = 0.1) when substrate movement is accounted for (orange) or not (blue). (d) Distributions of relative errors for the estimation of diffusion parameters for the substrate.
