Fig. 1: Frequency distribution of genes affected by driver mutations in prostate cancer. | Nature Communications

Fig. 1: Frequency distribution of genes affected by driver mutations in prostate cancer.

From: Somatic driver mutation prevalence in 1844 prostate cancers identifies ZNRF3 loss as a predictor of metastatic relapse

Fig. 1: Frequency distribution of genes affected by driver mutations in prostate cancer.

The full cohort (n = 1844) was split into localized (n = 1289) and metastatic (n = 555) disease. Estimated proportion of patients in each cohort harboring each of 113 specific driver mutations. X-axis indicates the gene or genomic locus affected. Bar color indicates the type of driver mutation affecting that gene. Several genes are affected by multiple mutation types (e.g. TP53, PTEN, and others). Bars show the proportion of patients harboring the indicated mutation. Error bars represent 95% confidence intervals. Centre of the error bars represent the observed proportion. Source data are provided as a Source Data file.

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