Fig. 5: Mouse liver chromatin is more accessible at night, synchronized with HNF4A recruitment.

a–c Heatmap of H3K4me1 ChIP-seq (a), H3K27ac ChIP-seq (b), or ATAC-seq (c) signals within liver tissues sampled at ZT16 (left) or ZT6 (right) and centered at all peaks of ZT16. Peaks are ordered vertically by signal strength. d KEGG pathway analysis was performed for genes having ZT16-ZT6-common or ZT16-enriched H3K4me1 peaks as defined in Supplementary Fig. 9c.