Fig. 3: Inhibition candidates for TcdA-GTD and TcdB-GTD catalytic activity.
From: Inhibition of Clostridium difficile TcdA and TcdB toxins with transition state analogues
Chemical structures of transition state analogues that were tested for inhibition of TcdA-GTD and TcdB-GTD in this study. Positions of relevant carbon atoms in isofagomine and noeuromycin are indicated.
