Fig. 4: Birth location enrichment maps reveal the historical habitation and migration of ancestors of genetic matches to AF risk allele carriers. | Nature Communications

Fig. 4: Birth location enrichment maps reveal the historical habitation and migration of ancestors of genetic matches to AF risk allele carriers.

From: The history and geographic distribution of a KCNQ1 atrial fibrillation risk allele

Fig. 4: Birth location enrichment maps reveal the historical habitation and migration of ancestors of genetic matches to AF risk allele carriers.The alternative text for this image may have been generated using AI.

Maps of Europe and North America showing enriched birth locations of ancestors of genetic matches to the original five AF subjects. Locations are colored by degree of overrepresentation (odd ratio ≥ 4), with at least 10 unique family trees for each location. Color indicates log2 odds ratio (OR), circle size indicates number of samples per location within a given time period, expressed as log10. The maps reveal the ancestral origin of the genetic matches centered in Denmark, followed by migration to the Eastern United States and then westward across the United States along known Mormon migration routes to Utah.

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