Fig. 4: Dissection and clustering of myeloid cells in MPE patients.
From: Single-cell analysis of diverse immune phenotypes in malignant pleural effusion
a t-SNE plots of myeloid cells within each cell type, color-coded by myeloid cell subsets. b Average proportion of each cell subset derived from each patient (left panel) and MPE or blood (right panel). c Dot plot of the average expression of canonical marker genes for myeloid cells. Y-axis: Seurat-clusters in Supplementary Fig. 4a. d The heatmap of M1 and M2 marker genes in monocytes or macrophages. e GO enrichment analysis between monocytes and macrophages. f The heatmaps show the genes differentially expressed in dendritic cell (DC) subsets. The statistical significance was tested by Fisher’s exact test and adjusted by Benjamini–Hochberg correction. g Diffusion map of myeloid cell subset functional state transitions.
