Fig. 5: Kinetic experiments. | Nature Communications

Fig. 5: Kinetic experiments.

From: Asymmetric construction of acyclic quaternary stereocenters via direct enantioselective additions of α-alkynyl ketones to allenamides

Fig. 5

a Relationship between the initial reaction rate and concentration of the CPA catalyst A7. b Relationship between the initial reaction rate and concentration of ketone 1a. c Relationship between the initial reaction rate and concentration of the allenamide 2a. d Relationship between the initial reaction rate and concentration of the amide additive 2a’. e KIE experiment of the α-H of ketone 1a. f Isomerization of 1a into allenyl ketone 1a’ and its reaction with allenamide 2a under the standard conditions.

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