Fig. 8: Large-scale reaction and derivatizations of the chiral products.

a Gram-scale reaction. b Hydrogenation of 3a. c Cycloaddition of 3a with organic azide. d Hydrolysis and aldol reaction of 3a. e Reduction and cyclization of 3a.

a Gram-scale reaction. b Hydrogenation of 3a. c Cycloaddition of 3a with organic azide. d Hydrolysis and aldol reaction of 3a. e Reduction and cyclization of 3a.