Fig. 8: Impact of HCoV immunity on COVID-19 severity. | Nature Communications

Fig. 8: Impact of HCoV immunity on COVID-19 severity.

From: Multifactorial seroprofiling dissects the contribution of pre-existing human coronaviruses responses to SARS-CoV-2 immunity

Fig. 8: Impact of HCoV immunity on COVID-19 severity.

a Association of hospitalization status (not hospitalized (N = 16); hospitalized not in ICU (N = 42); hospitalized in ICU (N = 22)) and high or low IgG HCoV reactivity. Rectangle sizes correspond to the proportion of included patients. b Influence of HCoV reactivity (low/high) on the hospitalization status in a subset of N = 80 patients, as estimated with odds ratios, in an ordinal regression (with levels = not hospitalized (N = 16); hospitalized not in ICU (N = 42); hospitalized in ICU (N = 22)) and a logistic regression (reference = not hospitalized (N = 16); versus all hospitalized (N = 64)). Data is presented as parameter estimation and its 95% confidence interval. Level of significance of the parameter is obtained with a two-sided t-test (p-value is displayed if <0.05, otherwise indicated as n.s.).

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