Fig. 1: Extensive within- compared to between-subject variance in genus abundances are reflected partly in alpha-diversity but not in beta-diversity measures. | Nature Communications

Fig. 1: Extensive within- compared to between-subject variance in genus abundances are reflected partly in alpha-diversity but not in beta-diversity measures.

From: Temporal variability in quantitative human gut microbiome profiles and implications for clinical research

Fig. 1

a Within- versus between-subject variance in absolute genus abundance (Wilcoxon test, two-sided, n = 96, P = 1.75 × 10−7) (left) and within-subject and between-subject variance as part of the total variance in genus abundance (right) for all genera over the abundance threshold. b Within- and between-subject variance as part of the total variance in alpha diversity measures, for observed richness, Pielou evenness, and Shannon diversity index based on QMPs. c Beta-diversity, as assessed through Bray Curtis dissimilarity, between samples of the same individual (800–821), and between the first sample of each individual (Bet) based on QMPs. Significance of the differences within and between individuals were tested through an ANOVA on multivariate homogeneity of group dispersions (N = 20, n = 694). The body of the box plots represents the first and third quartiles of the distribution, and the median line. Whiskers extend from the quartiles to the last data point within 1.5×IQR, with outliers beyond. Significance levels: ***: 0.001, **: 0.01, *: 0.05. The same figure based on RMPs can be found in Supplementary Fig. 2.

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