Fig. 5: Specific T cell responses. | Nature Communications

Fig. 5: Specific T cell responses.

From: Pediatric COVID-19 patients in South Brazil show abundant viral mRNA and strong specific anti-viral responses

Fig. 5: Specific T cell responses.The alternative text for this image may have been generated using AI.

A Gating strategies and typical plots of CD4+ and CD8+ T cells stimulated with peptide pools from structural proteins spike (S), membrane (M) and nucleocapsid (N), and analyzed by flow cytometry for cytokine production. B Comparisons of effector T cells in each group—percentages of CD4+ or CD8+ cells, producing IFNγ, TNF or IL-17 in response to stimulation by each peptide pool. Each dot represents a patient, color coded: purple for children; green for adults with mild disease and red for adults with severe disease. All analyses are Kruskal–Wallis tests, and the p values are indicated over brackets (n children = 10, n AMD = 9, n ASD = 13). Significant differences are indicated by p values in a higher font, the horizontal bar representing the median. Source data are provided as a Source Data file.

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