Fig. 8: Urate-associated CpGs that were associated with cardiometabolic and kidney traits. | Nature Communications

Fig. 8: Urate-associated CpGs that were associated with cardiometabolic and kidney traits.

From: Epigenome-wide association study of serum urate reveals insights into urate co-regulation and the SLC2A9 locus

Fig. 8: Urate-associated CpGs that were associated with cardiometabolic and kidney traits.

All traits that were included in the lookup are shown, including those without reported associations with urate-associated CpGs. Blue: positive association between DNA methylation and trait levels; Red: inverse association between DNA methylation and trait levels. BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, TG triglycerides, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, inc. incident, GGT Gamma-glutamyl transferase, ALT alanine aminotransferase, CRP C-reactive protein, eGFR estimate glomerular filtration rate. Genetic correlations were reported in Tin et al. Nat Genet 2019. *Genetic correlation between serum urate and hypertension was 0.39. No EWAS of hypertension was available; SBP and DBP were used instead.

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