Fig. 10: scRNA-seq revealed phagocytosis-related gene expression difference of astrocytes between ischemic and hemorrhagic stroke.
From: Stroke subtype-dependent synapse elimination by reactive gliosis in mice
a tSNE map showed the expression profiles of the striatum in control, ischemic and hemorrhagic mice, respectively. b Heatmap showed fold change of top 20 genes. c Dot plot showing MEGF10 and MERTK expression in astrocytes. d Bar chart showed phagocytosis-related GO and KEGG pathways that downregulated in hemorrhagic stroke (HS), as compared with ischemic stroke (IS). Representative terms were shown in rows and −log10 (p) in columns. e tSNE map showed subclusters of astrocytes in IS and HS. f Violin plots showed top marker genes in specific astrocyte subclusters. g Bar chart showed phagocytosis-related GO and KEGG terms enriched in subcluster 3 of astrocytes.
