Fig. 3: Scope with regard to the hydroxylamines in the synthesis of secondary anilines. | Nature Communications

Fig. 3: Scope with regard to the hydroxylamines in the synthesis of secondary anilines.

From: Hydroxylamine-mediated C–C amination via an aza-hock rearrangement

Fig. 3

Reaction conditions: alcohol (0.2 mmol), aminating reagents (0.3 mmol), HFIP (hexafluoroisopropanol) (1 mL), 12 h, r.t.; a2b (0.22 mmol); b1-(3,4-dimethoxyphenyl)ethan-1-ol (1ah, 0.2 mmol) instead of 1a; cTFE (trifluoroethanol) (1 mL) instead of HFIP; Ts toluenesulfonyl, Ms methanesulfonyl.

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