Fig. 5: Gene expression profile revealed some extent of similarity of the same histologic components across different patients. | Nature Communications

Fig. 5: Gene expression profile revealed some extent of similarity of the same histologic components across different patients.

From: The histologic phenotype of lung cancers is associated with transcriptomic features rather than genomic characteristics

Fig. 5

a Principal component analysis (PCA) of all histologic components based on gene expression data. b Heatmap of the top 500 most variable genes across the samples clustered by both genes and the samples. c Commonly upregulated and downregulated pathways comparing SCLC with LUAD across public datasets and in-house dataset. d Commonly upregulated and downregulated pathways comparing LCNEC with LUAD across public datasets and in-house dataset. Source data are provided as a Source Data file.

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