Fig. 5: Seeding propagates the high proteolytic resistance of ex vivo fibrils.
From: Cryo-EM demonstrates the in vitro proliferation of an ex vivo amyloid fibril morphology by seeding
Coomassie stained denaturing protein electrophoresis gels with seeded and unseeded in vitro fibrils, as well as with ex vivo fibrils, which were incubated with proteinase K for different periods of time as indicated in the figure. The lane next to the marker shows fibrils before proteinase K addition. All experiments were performed in triplicates (n = 3).
