Fig. 8: Combination treatment induced systemic anti-tumor immune response against CT26 tumor. | Nature Communications

Fig. 8: Combination treatment induced systemic anti-tumor immune response against CT26 tumor.

From: Yeast-derived nanoparticles remodel the immunosuppressive microenvironment in tumor and tumor-draining lymph nodes to suppress tumor growth

Fig. 8: Combination treatment induced systemic anti-tumor immune response against CT26 tumor.

A–B Individual (A) and average (B) tumor growth curves in untreated and treated groups of primary tumors, including UnTx group, aPD-L1 group, Small NPs group, combination group. C–D Individual (C) and average (D) tumor growth curves of distant tumors in four different groups (n = 4). E Photographs and (F–G) corresponding quantitative weight of primary tumors and distant tumors of four groups (n = 3). H Weight of mice in four groups during treatment (n = 4). Statistical significance was obtained by one-way ANOVA using the Tukey post-test. ****P < 0.0001; ***P < 0.005; **P < 0.01. Data are means ± SD.

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