Fig. 6: c-Fos-positive cells in the BLA and the ACC after the test session.

a, c, e Representative images of c-Fos expression 90 min after the test shown in Fig. 2b (panel a), Fig. 3b (panel c), and Fig. 5b (panel e). Scale bar, 100 μm. b, d, f Quantitative proportion of c-Fos-positive cells in the BLA (top) and ACC (bottom) (panel b: ArchT-Light OFF, n = 9 mice, ArchT-Light ON, n = 11 mice, EYFP-Light ON, n = 12 mice; panel d: ChR2-Light OFF, n = 11 mice, ChR2-Light ON, n = 12 mice, EYFP-Light ON, n = 7 mice; panel f: ArchT-Light OFF, n = 11 mice, ArchT-Light ON, n = 11 mice, EYFP-Light ON, n = 13 mice.) (one-way ANOVA followed by Tukey’s post hoc tests, panel b: BLA; P = 0.0002, ACC; P < 0.0001, panel d: BLA; P < 0.0001, ACC; P = 0.0002, panel f: BLA; P = 0.0001, ACC; P = 0.0120). Error bars indicate the mean ± s.e.m. *P < 0.05. For details of statistical data, see Supplementary Table 1. Source data are provided as a Source Data file.