Fig. 1: Challenges and strategies to access axially chiral styrenes bearing acyclic alkenes.
From: Carbene-catalyzed atroposelective synthesis of axially chiral styrenes

a Challenges in the synthesis of axially chiral styrenes bearing acyclic alkenes. b Previous methods for accessing axially chiral styrenes bearing acyclic alkenes. c Our Strategy: carbene-catalyzed chemo- and enantio-selective addition.