Fig. 8: FUMA GENE2FUNC analysis of 354 glycosylation enzymes and related genes in humans revealed a specific downregulation in the brain.
From: Mammalian brain glycoproteins exhibit diminished glycan complexity compared to other tissues
A Heat map demonstrating expression pattern of all glycosylation genes in humans, with a black bar above the 13 columns representing brain regions. B Tissue specific analysis showing down-regulation in the brain compared to all other 29 tissue types, with significant differentially expressed gene (DEG) sets using a two-sided t-test (Pbon < 0.05 and absolute fold change ≥ 0.58) highlighted in red.
