Fig. 4: Validation of the library using flow cytometry-FCM and independent artificial mixtures for adult peripheral blood. | Nature Communications

Fig. 4: Validation of the library using flow cytometry-FCM and independent artificial mixtures for adult peripheral blood.

From: Enhanced cell deconvolution of peripheral blood using DNA methylation for high-resolution immune profiling

Fig. 4

a and b Vaalidation of the EPIC IDOL-Ext. c and d Validation of the 450k IDOL-Ext. The area of each pieplot corresponds to the estimated proportion of the cell types within each group. Gran (Granulocytes) corresponds to the sum of Neu-neutrophils, Eos-eosinophils, and Bas-basophils. CD4T corresponds to the sum of CD4 + T cells naïve-CD4nv, memory-CD4mem and Treg. CD8T corresponds to the sum of CD8 + T-cells naïve-CD8nv and memory-CD8mem. B cell to the sum of the naïve-Bnv and memory-Bmem. No basophils were detected in the samples illustrated in a. Additionally, in a, “nonTcell” (Bnv, Bmem, and NK) were not experimentally measured. Source data are provided as a Source Data file.

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