Table 2 Estimates of per year increase in mutation density.
From: Age influences on the molecular presentation of tumours
Tumour-type | ΔMut/Mbp per year (95% CI) | ΔPGA per year (95% CI) |
|---|---|---|
Breast Carcinoma | 0.064 (0.029–0.95) | – |
Glioblastoma | 0.018 (−0.020–0.056) | – |
Head and Neck Carcinoma | 0.14 (0.071–0.21) | – |
Clear Cell Renal Cell Carcinoma | 0.018 (0.0084–0.027) | – |
Lung Adenocarcinoma | – | −0.17 (−0.24–0.10) |
Hepatocellular Carcinoma | 0.069 (0.032–0.11) | – |
Ovarian Cancer | – | 0.61 (0.41–0.81) |
Prostate Cancer | 0.12 (0.034–0.20) | 0.2 (0.13–0.27) |
Sarcoma | 0.044 (−0.0091–0.098) | – |
Stomach Adenocarcinoma | 0.31 (0.14–0.49) | 0.19 (0.064–0.31) |
Thyroid Cancer | 0.0082 (0.0066–0.0097) | 0.067 (0.036–0.098) |
Pan-cancer | 0.077 (0.049–0.10) | 0.010 (−0.01–0.030) |
