Fig. 4: In vivo experimental timeline.

The entire study is designed to last 6 weeks. On surgery day, we measured the intracranial pressure (ICP), induced the intraventricular hemorrhage (IVH), and implanted a ventriculoperitoneal shunt. The computed tomography (CT) scan was performed before and after the surgical procedure, to measure the ventricular size and confirm ventricular catheter placement. Magnetic actuation (30 min) was performed for the Treated group immediately afterward. At weeks 1, 3, and 5, each surviving animal was subjected to 30 min of magnetic field and CT scans. All surviving animals were terminated at week 6 for explantation and necropsy.