Fig. 6: Bioreactor fermentation of β-carotene and lycopene engineered Strains.
From: Removal of lycopene substrate inhibition enables high carotenoid productivity in Yarrowia lipolytica
a, d Fermentation profiles of the β-carotene-producing strain YLMA15 (a) and lycopene-producing strain YLMA34 (d) in a 3-L bioreactor. b, e β-carotene cultures displayed a deep red-orange color after 240 h cultivation (b), while lycopene cultures displayed a deep red color (e). c, f Microscopic images of cells producing β-carotene (c) and lycopene (f). β-carotene and lycopene are shown to accumulate intracellularly and dispersed throughout the cytoplasm in the most cells. For a and d, The average and s.d. of three biologically independent experiments are shown. For c and f, Three independent experiments were repeated with similar results. Source data are provided as a Source Data file.
