Fig. 3: Higher viral loads in samples with R203K/G204R SNPs. | Nature Communications

Fig. 3: Higher viral loads in samples with R203K/G204R SNPs.

From: SARS-CoV-2 genomes from Saudi Arabia implicate nucleocapsid mutations in host response and increased viral load

Fig. 3

a Top: The numbers of samples from Saudi Arabia presented in this study are shown as bars by their sampling date (January 2020–March 2021). Bottom: Samples deposited in GISAID. On both plots, lines show the fraction of samples having the R203K/G204R SNPs (red line), having both the R203K/G204R SNPs and the Spike protein N501Y SNP (blue line), and having the Spike protein D614G SNP (green line). b Overview of the three SNPs underlying the N protein R203K/G204R changes. Amino acid numbers in the N protein are shown above. c Density distributions of virus copy numbers derived from Ct measurements. Ct values from the N1 primer pairs were normalized by RNase P primer pair values and converted to copy numbers from a standard curve. Only samples processed using the TaqPath™ kit (Thermofisher) were included (see Methods).

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