Fig. 6: Hematopoietic Grx1 deficiency promotes formation of nitrotyrosine in the aortic root of aged female but not male mice. | Nature Communications

Fig. 6: Hematopoietic Grx1 deficiency promotes formation of nitrotyrosine in the aortic root of aged female but not male mice.

From: Glutaredoxin 1 controls monocyte reprogramming during nutrient stress and protects mice against obesity and atherosclerosis in a sex-specific manner

Fig. 6

a Representative images of aorta root sections stained with an antiserum against nitrotyrosine from 18-month-old male and female WT and Grx1-/- mice maintained on a normal chow diet for 18 months. Scale bar: 500 μm. Inserts: 100x magnification. b Nitrotyrosine levels measured in the aortic root of male and female WT and Grx1-/- mice maintained on a normal chow diet for 18 months. All data are expressed as mean ± S.D, n = 5–6 per group, 8 aortic root sections per mouse. Source data are provided as a Source Data file.

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