Fig. 9: Hematopoietic Grx1 deficiency exacerbates nutrient stress-induced monocyte dysfunction. | Nature Communications

Fig. 9: Hematopoietic Grx1 deficiency exacerbates nutrient stress-induced monocyte dysfunction.

From: Glutaredoxin 1 controls monocyte reprogramming during nutrient stress and protects mice against obesity and atherosclerosis in a sex-specific manner

Fig. 9

a MKP-1 activity in purified peritoneal macrophages isolated from HCD-fed female LDLR-/-Grx1Leuko-/- mice (Grx1Leuko-/-) and age-matched female LDLR-/- mice (WT). n = 15 mice per group. b Chemotaxis of purified peritoneal macrophages isolated from female Grx1Leuko-/- and age-matched C57BL/6 mice (WT). n = 4 mice per group. All data are expressed as mean ± S.D. One-way ANOVA followed by Fisher’s Least Significance Difference test were used to compare the mean values between experimental groups. Source data are provided as a Source Data file.

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