Fig. 1: Characterization of the aged human SVZ at the transcriptome level. | Nature Communications

Fig. 1: Characterization of the aged human SVZ at the transcriptome level.

From: Single-cell profiling of human subventricular zone progenitors identifies SFRP1 as a target to re-activate progenitors

Fig. 1

a UMAP plot identifies seven clusters of cells, corresponding to two progenitor clusters, one neuronal, and three microglia clusters. b Feature plots showing the expression of canonical markers for the clusters: Progenitor 1 and 2 (SOX2; SOX10), Neuronal (RBFOX1; MAP2), and Microglia 1, 2, and 3 (CX3CR1; AIF1). c Feature plots showing the absence or presence of markers for ependymal, radial glial cell (RGC), early progenitor, late progenitor, astrocytes, oligodendrocyte progenitor cell (OPC) lineage and microglia. (n = 3 donors; 2 females, aged 95 (504 cells) and 96 years (118 cells); 1 male, aged 72 years (116 cells)).

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