Fig. 3: Increased expression of cell cycle inhibitors in OPCs from the aged human SVZ. | Nature Communications

Fig. 3: Increased expression of cell cycle inhibitors in OPCs from the aged human SVZ.

From: Single-cell profiling of human subventricular zone progenitors identifies SFRP1 as a target to re-activate progenitors

Fig. 3

a Dot plot showing the expression level (red = high, blue = low) and percentage of cells expressing markers of the oligodendroglial lineage. b, c Violin plots of markers for proliferation and cell cycle progression (b) and of markers for quiescence and cell cycle inhibition (c) in cells from the OPC lineage from Zhong et al.39, Jäkel et al.42, and present study (Donega et al.). (n = 3 donors; 2 females, aged 95 (504 cells) and 96 years (118 cells); 1 male, aged 72 years (116 cells)).

Back to article page