Fig. 2: Circulating viral content is associated with clinical characteristics. | Nature Communications

Fig. 2: Circulating viral content is associated with clinical characteristics.

From: Circulating microbial content in myeloid malignancy patients is associated with disease subtypes and patient outcomes

Fig. 2: Circulating viral content is associated with clinical characteristics.

a Individual species among the top 1/3 of patients with regard to viral burden. b All controls are shown with their corresponding detected viruses, on the same (logarithmic) scale as panel a, for comparison. Only the leftmost four samples had any detectable viral species. c The prevalence of viral species (those found in >1% of cases are shown). d Presence of EBV (192 patients with EBV, 448 without) is associated with worse survival in MDS patients (HR and P-value are age-adjusted). E The Kaplan–Meier curves for intermediate (n = 135), low (n = 224), and very low (n = 92) IPSS-R categories. f As in panel e, but the low category is stratified by EBV status. Low-risk patients with (n = 59) and without (n = 165) EBV become statistically indistinguishable from the intermediate-risk and very low-risk categories, respectively. Two-sided P-values are computed using the Wald test applied to the Cox proportional hazards model. EBV Epstein-Barr virus; HCMV human cytomegalovirus.

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