Fig. 5: Associations between myeloblast percentage and microbial characteristics. | Nature Communications

Fig. 5: Associations between myeloblast percentage and microbial characteristics.

From: Circulating microbial content in myeloid malignancy patients is associated with disease subtypes and patient outcomes

Fig. 5

a Viral read presence is associated with lower blast percentage. Here 868 patients have virus present and 296 patients have virus absent. P-value from two-sided Wilcoxon test. In boxplots, bounds of box indicate first and third quartiles, center line indicates median, and whiskers extend to (first quartile −1.5 × IQR) and (third quartile +1.5 × IQR) or extrema, whichever is less extreme (here IQR = interquartile range, i.e. third quartile–first quartile). b Viral burden are both associated with lower blast percentage. c Proteobacteria relative abundance is positively correlated with blast percentage. d–i For most taxonomic levels, α-diversity is negatively correlated with blast percentage. j AUROCs for random forest classification of patients (n = 1164) above/below various blast percentage thresholds, with mean over 1000 independent training/test splits indicated in black and 95% confidence intervals indicated with gray shading. In panels b–i, green indicates MDS patients (n = 638), salmon indicates AML patients (n = 526), shading indicates the 95% confidence interval, and P-values are from two-sided Spearman correlation test.

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