Fig. 3: MEP assay of the pure compounds from the hexane extract of Psoralea corylifolia.
From: The flavonoid corylin exhibits lifespan extension properties in mouse
a–i Visualization curve of haploid MEP strain ZHY1 in liquid YEPD containing (1) psoralen (n = 4), (2) isopsoralen (n = 4), (3) psoralidin (n = 5), (4) 2′,3′-dihydro-2′,3′-dihydroxypsoralidin (n = 5), (5) dehydroisopsoralidin (n = 7), (6) (+)-bakuchiol (n = 6), (7) bavachinin (n = 5), (8) bavachin (n = 5), (9) chromenoflavanone (n = 5), (10) daidzen (n = 6), (11) neocorylin (n = 6), (12) corylin (n = 6), (13) corylifol A (n = 6), (14) neobavaisoflavone (n = 5), (15) 7-hydroxy-3(2-(2-hydroxypropan-2-yl)benzofuran-5-yl)-4H-chromen-4-one (n = 6), (16) (2″S)-2″,3″-dihydroxyisopentyl-daidzein (n = 6), (17) 6-prenyl-fisetin (n = 6), (18) 3″-hydroxy-isopentyl-isoliquiritigenin (n = 3), (19) isobavachromene (n = 3), (20) psorachromene (n = 3), (21) 4-methoxybavachalcone (n = 5), and (22) isobavachalcone (n = 4). Cultures were incubated at 30 °C for 60 h. The viability is presented as CFUs per 500 μl, and this value was determined by harvesting samples at the indicated time points. Data presented as mean ± SD from at least three independent experiments. p values were determined by one-way ANOVA (multiple comparisons). Source data are provided as a Source data file.
