Fig. 3: Tissue-specific eQTL and TWAS signals at the 17q21 asthma locus. | Nature Communications

Fig. 3: Tissue-specific eQTL and TWAS signals at the 17q21 asthma locus.

From: Nasal airway transcriptome-wide association study of asthma reveals genetically driven mucus pathobiology

Fig. 3

a Bar plots of different tissue COA TWAS p values (two-sided) for GSDMB, IKZF3, and ORMDL3. b Local Manhattan plot of COA GWAS on the 17q21 chromosomal region (top). Miami plots comparing whole blood (blue) and nasal epithelium (red) eQTL signals on three 17q21 genes: GSDMB, IKZF3, and ORMDL3. P values were obtained from two-sided tests.

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