Fig. 1: Single cell RNA sequencing of tumor-infiltrating B-cells.
From: Tertiary lymphoid structures critical for prognosis in endometrial cancer patients
a UMAP projection of endometrial cancer B-cell scRNA-seq data (1501 cells; 6 donors) annotated by cluster. b Dotplot of canonical B cell subtype marker genes per cluster. c Predicted cell identity for Cluster 1, Cluster 2 and Cluster 3 cells assigned using reference scRNA-seq data of a human lymph node. Cell identities are projected onto the endometrial cancer B-cell UMAP from a. d Quantification of predicted cell identities per cluster. e UMAP projection of Cluster 3 plasmablasts with Feature Plots depicting IGHG1, IGHA1, IGLC3 and IGKC expression in single cells. UMAP Uniform Manifold Approximation and Projection; MBC Memory B cell. Source data are provided as a Source Data file.
