Fig. 4: The 1952 of the 2030 metabolite genetic association signals identified in stepwise conditional tests with SPIP ≥ 0.95 in DAP-g Bayesian fine mapping. | Nature Communications

Fig. 4: The 1952 of the 2030 metabolite genetic association signals identified in stepwise conditional tests with SPIP ≥ 0.95 in DAP-g Bayesian fine mapping.

From: Genome-wide association studies of metabolites in Finnish men identify disease-relevant loci

Fig. 4

a Numbers of variants in the 95% credible sets and distribution of variant posterior inclusion probabilities (VPIPs) for the most likely causal variants within the 95% credible sets. b Density plot of largest VPIPs highlights the variants with > 10-fold greater frequency in METSIM than non-Finnish Europeans (gnomAD v3.1; blue) have larger VPIPs than all other variants (maize).

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