Fig. 1: Design and characterization of DNA-based bioorthogonal catalyst.
From: DNA-based platform for efficient and precisely targeted bioorthogonal catalysis in living systems
a Illustration of the design and synthesis of DNA-templated CuNPs as bioorthogonal catalyst. b Aptamer-mediated CuNPs for cell-specific identification and targeted cancer therapy in vivo; (c) Transmission electron microscopy (TEM) image of Apt-Cu30. d, e High-resolution TEM images of Apt-Cu30. f Histogram of size distribution of Apt-Cu30. The total number of nanoparticles counted was 100. g Zeta-potentials of Apt-Cu20, Apt-Cu30, and Apt-Cu40 in H2O (pH 6.6). Data were presented as mean ± SD (n = 3 independent experiments). h XPS spectra of Apt-Cu30 (red line: fitting curve). i Fluorescence spectra of Apt-Cu20, Apt-Cu30 and Apt-Cu40 excited at 340 nm. (Inset) Photographs of Apt-Cu under UV lamp. Source data are provided as a Source Data file.
