Fig. 7: CITE-On data processing of never-before-seen recordings. | Nature Communications

Fig. 7: CITE-On data processing of never-before-seen recordings.

From: A deep-learning approach for online cell identification and trace extraction in functional two-photon calcium imaging

Fig. 7

a Median projection of a representative t-series from the ABO dataset showing GCaMP6f expressing cortical neurons. CITE-On true positives (CITE-On, green) and true positives provided by the Allen Brain Observatory (ABO, magenta) are shown. b Same as in a with CITE-On true positives (green) and STNeuroNET true positives (magenta). c Superposition of CITE-On (green), ABO (magenta), and STNeuroNET (cyan) true positives. d Left: 24 representative cells detected by CITE-On and identified as true positives in ABO and STNeuroNET. The CITE-On-identified bounding box is represented in green. Right: corresponding CITE-On extracted fluorescence traces. e Same as in d for four representative CITE-On only cells. These fours cells were not included in the GT of the ABO dataset and of the STNeuroNET GT reported in the ref. 22, either as true or false positives. f Cross-correlation matrix for all functional traces extracted from true positive (TP) detections in the t-series displayed in a. Cell identities are grouped with hierarchical dendrogram sorting. The pseudocolor scale indicates the cross-correlation value.

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