Fig. 4: Tissue-specific metabolic phenotypes of the HSD hits.
From: Genetic variation of macronutrient tolerance in Drosophila melanogaster
a The relative point (normalized to control) at which 50% of larvae pupated under tissue-specific knockdowns (Cg-GAL4, Mef2-GAL4 and NP1-GAL4) of HSD hits. n = minimum of 3 vials (each with 30 larvae) per diet and genotype. Error bars display SD. See Source Data file for statistical analyses and exact p-values. b Relative resting rate of energy metabolism (mJ h−1) of Cg-GAL4 knockdown of HSD hits (normalized to control HPD), n = minimum of 3 flies per diet and genotype. Error bars display SD. Statistical significances were calculated using the two-way ANOVA in conjunction with Dunnett’s multiple comparisons test (by genotype) and with Šídák’s multiple comparisons test (by diet). Data are presented as mean values +/− SD. * p = 0.0348 (Dunnett’s multiple comparisons test), # p = 0.004 (Šídák’s multiple comparisons test). Source data are provided as a Source Data File.
