Fig. 5: ComK binds to and induces the expression of competence and glucose-uptake genes.
From: The induction of natural competence adapts staphylococcal metabolism to infection
A Binding of ComK to regulatory regions of several transcriptional units (comG, ackA, glcA, glcB, glcC, glcU, uhpT, pgm, cidC, pfkA). comG and ackA represent positive and negative controls, respectively. The reference front of unbound DNA is marked with an R. Shifted DNA samples bound to ComK are marked with S. These results are representative of the results obtained in three independent experiments. B Growth determination (CFU/ml) in H2O2-treated SMM cultures (37 °C and 200 rpm agitation) supplemented with glucose or S. aureus DNA (gDNA) as a nutrient source. Control sample had no glucose or DNA added. Statistical significance was measured by one-sided ANOVA with Tukey’s test for multiple comparison. Data are shown as mean ± SD of three independent experiments (n = 3). Source data are provided as a Source Data file.
