Table 1 Characteristics of patients’ samples.

From: Comparison of clonal architecture between primary and immunodeficient mouse-engrafted acute myeloid leukemia cells

Variables

 

Engraftment

Failure

P-valuea

Number (%)

 

105 (66%)

55 (34%)

 

Patient age, median (range)

65 (18–92)

64 (24–86)

0.621

Disease

de novo AML

84

41

0.373

 

FAB classification

   
 

M0

2

1

0.028

 

M1

15

5

 
 

M2

14

17

 
 

M3

8

5

 
 

M4

38

9

 
 

M5

6

3

 
 

M6

1

0

 
 

M7

0

1

 
 

AML with MRC

12

12

 
 

tAML from MPN

6

2

 
 

AL of ambiguous lineage

2

0

 
 

CML-BC

1

0

 

Cytogenetic risk

Favorable

10

14

0.053

 

Intermediate

48

25

 
 

Poor

37

16

 
 

Not examined

10

0

 

ELN risk categoryb

Favorable

10

11

0.022

 

Intermediate

21

17

 
 

Adverse

59

20

 
 

unknown

7

2

 

Graft source

BM/PB

69/36

44/11

0.060

Sample

New/relapse/refractory

58/29/18

48/5/2

<0.001

Infused cell count

≥ 5 × 106

95

39

0.001

 

< 5 × 106

10

16

 

Infused blast %, median (range)

58.4 (1–100)

46.3 (3–99.5)

0.280

Engraft day, median (range)

106 (27–380)

-

-

  1. aChi-square test for Graft source, Fisher’s exact test for other categorical data and the Mann–Whitney U-test for continuous variables.
  2. bAPL excluded.
Back to article page