Fig. 8: Mechanistic studies.
From: Silver-catalyzed site-selective C(sp3)−H benzylation of ethers with N-triftosylhydrazones
a One-pot competition KIE experiment. b Computed energy profiles for the silver-catalyzed carbene insertion into C–H bonds of methyl isoamyl ether. c Optimized geometrical structures for transition state structures. Calculations were performed at the M06/[6–31 + G(d,p)/SDD(Ag)] level of theory in chloroform within the SMD model. Energies are given in kcal mol−1 and distances in angstroms.
