Fig. 5: A functional map of HIV-host interactions.
From: A functional map of HIV-host interactions in primary human T cells
HIV proteins (yellow) are connected by blue edges to protein–protein interactors; black edges connect known human complexes (Corum database)77; dotted lines represent annotated HIV-host PPIs in the VirusMint database78. Candidate dependency and restriction factors are represented as blue and red nodes, respectively. Candidate host factors with early-acting or late-acting phenotypes have green or brown halos, respectively. Factors with no functional role in HIV infection observed here are light gray, while those of undetermined phenotype are dark gray. Figure is adapted from23.
