Table 1 Aggregate ROI analyses of mentalizing.

From: Electrocorticographic evidence of a common neurocognitive sequence for mentalizing about the self and others

 

Onset (ms)

Peak (ms)

Offset (ms)

Duration (ms)

Peak Power (z)

Type Other-Self

b

SE

p

b

SE

p

b

SE

p

b

SE

p

b

SE

p

Visual

−4

3

0.230

2

7

0.731

10

14

0.456

7

19

0.718

0.025

0.013

0.058

TPJ

1

14

0.962

11

46

0.808

2

28

0.951

4

28

0.886

0.002

0.017

0.901

ATL

16

18

0.376

80

30

0.007

58

26

0.026

71

28

0.013

0.021

0.012

0.091

PMC

−12

7

0.088

71

15

<0.001

112

18

<0.0001

101

40

0.011

0.251

0.045

<0.001

amPFC

34

28

0.230

182

30

<0.001

151

13

<0.001

158

21

<0.001

0.013

0.074

0.857

dmPFC

20

18

0.279

189

45

<0.001

130

9

<0.001

130

20

<0.001

0.023

0.041

0.569

vmPFC

21

37

0.571

203

63

0.001

160

18

<0.001

193

52

<0.001

0.147

0.154

0.341

RT Behav

b

SE

p

b

SE

p

b

SE

p

b

SE

p

b

SE

p

Visual

0.004

0.002

0.021

0.006

0.004

0.143

0.897

0.006

<0.001

0.239

0.015

<0.001

0.014

0.008

0.106

TPJ

0.025

0.005

<0.001

0.292

0.023

<0.001

0.904

0.014

<0.001

0.143

0.016

<0.001

0.085

0.018

<0.001

ATL

0.009

0.008

0.272

0.270

0.023

<0.001

0.772

0.015

<0.001

0.096

0.011

<0.001

0.020

0.012

0.086

PMC

0.017

0.007

0.012

0.336

0.493

<0.001

0.853

0.023

<0.0001

0.209

0.012

<0.001

0.033

0.018

0.060

amPFC

0.041

0.015

0.006

0.428

0.024

<0.001

0.970

0.008

<0.001

0.158

0.018

<0.001

0.037

0.021

0.076

dmPFC

0.038

0.008

<0.001

0.426

0.021

<0.001

0.987

0.007

<0.001

0.183

0.015

<0.001

0.086

0.013

<0.001

vmPFC

0.010

0.019

0.604

0.407

0.105

<0.001

0.987

0.015

<0.001

0.197

0.041

<0.0001

0.058

0.090

0.521

Choice True-False

b

SE

p

b

SE

p

b

SE

p

b

SE

p

b

SE

p

Visual

0

3

0.991

−21

12

0.079

−11

8

0.141

−21

14

0.138

−0.025

0.013

0.058

TPJ

−2

14

0.911

−14

28

0.616

−20

21

0.347

−16

25

0.509

0.021

0.031

0.504

ATL

−9

20

0.651

−21

34

0.548

−12

21

0.563

−21

20

0.278

−0.017

0.022

0.447

PMC

−10

10

0.355

−5

16

0.765

−3

15

0.848

−03

20

0.869

−0.010

0.023

0.650

amPFC

19

25

0.463

−43

34

0.206

−13

17

0.451

−36

29

0.221

−0.021

0.028

0.444

dmPFC

16

15

0.312

−27

28

−0.334

−21

9

0.020

−27

13

0.040

−0.076

0.030

0.011

vmPFC

26

44

0.562

−50

53

0.350

−10

25

0.686

0−50

48

0.300

−0.006

0.041

0.875

  1. Regions-of-interest (ROI) are defined in Fig. 1c. Significant p-values are bolded (p < 0.05, uncorrected, two-tailed). Linear mixed-effect modeling (LMEM) was used to analyze single-trial activation metrics (see Fig. 1e) from mentalizing-active ROI sites (see Fig. 3a). LMEMs controlled for stimulus visual dissimilarity (see Supplementary Methods) and accounted for site- and participant-related heterogeneity by nesting effects within Site and Participant. Separate LMEMs were used per ROI and activation metric (full details in Methods). TypeOther-Self indicates mentalizing type differences, controlled for RTBehav (Fig. 5c–e). RTBehav indicates behavioral response time effects, controlled for behavioral response choices (Fig. 4d, e). ChoiceTrue-False indicates behavioral response choice differences, controlled for RTBehav (task in Fig. 1a). N per ROI (trials x sites): Visual = 8453, TPJ = 3189, ATL = 3046, PMC = 4301, amPFC = 2012, dmPFC = 3438, vmPFC = 1060. Abbreviations: ms = millisecond, z = z-score, b = slope estimate, SE = standard error of b, Visual = visual cortex, ATL = anterior temporal lobe, TPJ = temporoparietal junction, PMC = posteromedial cortex, amPFC = anteromedial prefrontal cortex, dmPFC  = dorsomedial prefrontal cortex, vmPFC = ventromedial prefrontal cortex. Source data are provided as a Source Data file.