Table 1 List of all pockets observed after probe docking, their approximate locations, and classes for which the densities are visible.
From: The pocketome of G-protein-coupled receptors reveals previously untargeted allosteric sites
Site | Locationa | Class |
|---|---|---|
OS1 | UP OF I,II | A, B1, B2, C, D1, F |
OS2 | LP OF I,II | A, B1, B2, C, D1 |
OS4 | MP OF V,VI | B1, B2, C, D1, F |
OS5 | MP-LP OF V,VI | A, B1, B2, C, D1, F |
OS6 | UP OF VI,VII | A, B1, C, F |
OS7 | UP OF I,VII | A, B1, B2, C, D1, F |
OS8 | MP OF I,VII | A, B1, B2, C, F |
OS9 | LP OF I,VII,VIII | A, B1, B2, C, D1, F |
OS10 | LP OF I,VIII | A, B1, C, F |
IBS1 | UP-MP IF | A, B1, B2, C, D1, F |
IBS2 | UP IF Above IBS1 IV,V, VI | A, B2, C |
IBS3 | UP IF Next to IBS1 I,II,III,VII | A, B1, C, D1 |
SODIUM | MP IF I,II,III,VI,VII | A, B1, C, D1, F |
GPROT | LP IF II,III,V,VI | A, B1, B2, C, D1, F |
KS1 | UP OF II,III | A, B1, B2, C, D1, F |
KS2 | UP OF III,IV | A, B1, B2, C, D1, F |
KS3 | MP-LP OF II,IV | A, B1, B2, C, D1, F |
KS4 | UP OF IV,V | A, B1, B2, C, D1, F |
KS5 | MP-LP OF III,IV,V | A, B1, B2, C, D1, F |
KS6 | LP OF IV,V | A, B1, C, D1, F |
KS7 | MP OF VI,VII | A, B1, B2, C, F |
KS8 | LP OF VI,VII | A, B1, C, D1, F |
KS9 | LP OF VII,VIII | A, B1, C, D1 |
KS10 | MP IF III,V,VI | B1, B2 |
KS11 | LP IF I,II,VII,VIII | A, B1, B2, C, D1, F |
KS12 | UP OF V,VI | A, B1, B2, C, D1, F |
