Fig. 1: Enantioselective construction of vicinal tertiary and all-carbon quaternary stereocenters.

a Vicinal 3° and all-carbon 4° stereocenters in pharmaceutical agents. b Doubly stereoconvergent approaches to make vicinal stereocenters. c Cu/Mg-dual catalytic APS reaction to make vicinal 3° and 4° stereocenters (this work).