Fig. 5: PCA suggests that the p38 and p53-signaling states exist pretreatment and increase in weight over time. | Nature Communications

Fig. 5: PCA suggests that the p38 and p53-signaling states exist pretreatment and increase in weight over time.

From: Visual barcodes for clonal-multiplexing of live microscopy-based assays

Fig. 5: PCA suggests that the p38 and p53-signaling states exist pretreatment and increase in weight over time.

A PCA of the activity scores of 11 signaling pathways after 48 h of treatment with 122 drugs. The color of each drug is indicating its cluster in Fig. 3A. B, C Bar plots representing the PC1 loading of each pathway after 48 h of drug treatment (B) or pretreatment (C). D Variance of pathway activity, when projected on the principal components calculated from measurements on cells that were not exposed to drug treatment. Source data are provided with this paper.

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